Protein A for Monoclonal Antibody Titer Measurements with ACQUITY Arc Bio, Alliance, and ACQUITY UPLC H-Class Bio Chromatography Systems

[ APPLICATION NOTE ] Evaluating the Performance of the ACQUITY Arc Bio UHPLC System for the Size-Exclusion Chromatography Analysis of a Monoclonal Antibody Corey E. Reed, Stephan M. Koza, and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■…

[ TECHNOLOGY BRIEF ] Charge Variant Analysis of Infliximab on the Alliance, ACQUITY Arc Bio, and ACQUITY UPLC H-Class Bio Liquid Chromatography Systems Using a Quaternary pH Gradient Corey E. Reed, Stephan M. Koza, and Weibin Chen, Waters Corporation, Milford,…

METHOD TRANSFER AND ROUTINE ANALYSIS OF PROTEIN AND PEPTIDE-BASED DRUG PRODUCTS USING A BIOCOMPATIBLE UHPLC SYSTEM Brooke M. Koshel, Robert Birdsall, Corey Reed, Stephan Koza, Zhimin Li, Paula Hong, Joe Fredette, and Scott Berger Waters Corporation INTRODUCTION Many of the…

[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…